Immune system research and clinical trials
Throughout this book I’ve summoned fifty years of medical experience to advance the notion that unabated stress alters our body functions and makes development of life-threatening, chronic disease more likely. I’ve drawn attention to the science of...
Silicon Isn’t Just for Computers. It Can Make a Good Kidney, Too
Layman's summary: Now, after more than 20 years of work, one team of doctors and researchers is close to offering patients an implantable artificial kidney, a bionic device that uses the same technology that makes the chips that power your laptop and smartphone....
Role of impaired Nrf2 activation in the pathogenesis of oxidative stress and inflammation in chronic tubulo-interstitial nephropathy
Layman's summary: Tubulo-interstitial nephropathy is a disease process found in many patients especially those who have been on dialysis for long periods of time. In research on rats, there is a possible suggestion that dietary changes can affect the causes of the...
Oral activated charcoal adsorbent (AST-120) ameliorates CKD-induced intestinal epithelial barrier disruption
Layman's summary: The study suggest that oral activated charcoal adsorbent may be also effective in attenuating oxidative stress and inflammation which are the main cause of accelerated cardiovascular disease and numerous other complications in patients with end stage...
Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis
Layman's summary: There is the potential for a blood screening for kidney disease. Publication date: July 2011 Published in: Nature Medicine Lead author: Changli Wei Department of Medicine, Miller School of Medicine University of Miami Abstract: Focal segmental...
The Leaky Gut and Altered Microbiome in Chronic Kidney Disease
Publication date:November 2017 Layman's summary: The efforts to reduce high levels of phosphorus and potassium in dialysis patients adversly affects the good microbial bacteria in the GI tract. Published in: Journal of Renal Nutrition Lead author: Wei Ling Lau...
Role of urea in intestinal barrier dysfunction and disruption of epithelial tight junction in chronic kidney disease.
Layman's summary: Research indicates that there are opportunities to improve dialysis through longer dialysis regimes and low-protein diets. Publication date: December 2013 Published in: American Journal of Nephrology Lead author: Nosratola D. Vaziri- Emeritus...
Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial
Layman's summary: A panel of British physicians published encouraging results regarding reversing diabetes Publication date: February 2018 Published in: The Lancett Lead author: Michael Lean et al University of Glasgow School of Medicine Abstract: The study was done...
Kidney disease and GI flora
Layman's summary: A function of normal kidneys is to maintain a synergistic balance of the myriad species of bacteria that reside in our gastrointestinal tract. When the balance of the trillions of bacteria is optimal, our immune system is strengthened, our mood is...
High Amylose Resistant Starch Diet Ameliorates Oxidative Stress, Inflammation, and Progression of Chronic Kidney Disease
Layman's summary: Maintaining a high resistant starch diet potentially could slow kidney disease by maintaining proper bacterial balance in the intestinal tract. Publication date: December 2014 Published in: PLOS One Lead author: Nosratola D. Vaziri-...