Layman’s summary: Maintaining a high resistant starch diet potentially could slow kidney disease by maintaining proper bacterial balance in the intestinal tract.
Publication date: December 2014
Published in: PLOS One
Lead author: Nosratola D. Vaziri- Emeritus Professor of Medicine
University of California Irvine
Former Chief, Division of Nephrology and Hypertension and former Chairman of Department of Medicine, Medicine School of Medicine

Abstract: Inflammation is a major mediator of CKD progression and is partly driven by altered gut microbiome and intestinal barrier disruption, events which are caused by: urea influx in the intestine resulting in dominance of urease-possessing bacteria; disruption of epithelial barrier by urea-derived ammonia leading to endotoxemia and bacterial translocation;

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